Beginner Tips

Settings
If this is your first time playing No Man's Sky:
• There are multiple game modes available, with different difficulty presets. Creative, Relaxed, Normal and Survival game mode saves can all play with each other, while Permadeath and Expedition game modes are separate.
• Go to Options > Network, and disable ability of other players to damage you, edit your bases, or edit your base terrain (discourages griefers). See multiplayer visual guide ».
• Excluding content designed with multiplayer in mind, progress isn't shared between players. It is in fact recommended to play the main (tutorial) missions with multiplayer disabled to prevent issues, at least until you unlock access to the Space Anomaly.
• If you are on PC and want to use the Plasma or Geo Cannon weapons, you might want to re-map secondary fire bind to be anything but RMB, since RMB is also hard-coded to "exit menu."

General Tips
• Save often: update your Restore Point by exiting the starship, claiming a Base Computer, interacting with a Save Point/Save Beacon, or the waypoint machines you find at some Points of Interest (POIs).
• Sentinels are like police in NMS: they don't like it when you destroy, mine or harvest rocks or plants from a planet. When they're watching, stop or move away from them to resume harvesting resources. Avoid entering your ship with an active Sentinel Alert Level: sentinel ships are more difficult to evade than planet sentinels. For tips on how to evade sentinels, take a look at this post.
• The Space Anomaly NPCs and terminals are the single biggest source to learn technology or base part blueprints.
• To easily return to a system or planet you like, place and claim a base computer and name it something you will remember.
• Storage upgrades can be applied to exosuit, ships, multi-tools and freighter. To apply a storage upgrade to a different inventory, switch inventory by pressing Q or E (dpad left or right), then apply the storage upgrade. Storage upgrades can be purchased with units, but also obtained from other sources like scrapping ships or mission board rewards.
• Discovering and registering the complete list of fauna on a planet (at once) will reward nanites - 250 per fauna.
For more inventory management tips, See this post ».

Missions
It's strongly recommended to play the entire main storyline, Artemis Path, and the Atlas Path. Playing all the "important" quests (Artemis path, The Atlas Path, The Space Anomaly, the Base Computer Quest, and Expanding the Base quests) will:
• Introduce you to many of the game's mechanics.
• Teach you unique tech and abilities you can't get anywhere else.
• Give you a lot of free tech you'd have to buy at the Space Anomaly otherwise.
The active mission will switch between available missions in the Logs. It can be well timed or random. You need to reselect the desired mission in the Log menu to continue.