I was leaving the Museum after donating 2 items back to back and after running around a bit of the court yard all the building were missing after loading in. So far this has only happened once and was resolved by teleporting using the stone statues. Came back to main area and the buildings were back so isn't game breaking but I thought it was important to mention.
Platform/verson/input: Steam, v1-1225, keyboard and wireless mouse
Save file named Evelyn.