Slayer Study: discover and promptly exterminate every creature in the bestiary.
Mapping Master: discover every Point of Interest.
All The Things I Feel: obtain one of every protection heart.
Fool's Folly: Take damage from traps 5 times in a single delve (arrows, spikes, magic ball shooters)
The Green Flood: spawn enough slimes during the king slime battle to trigger his invulnerability.
Powerful Pruning: destroy all four eye stalks in the first phase of the beast fight within 5 seconds (timer starts when the eyes start attacking).
Feeling Adventurous: enter every alternate floor in one run.
Not Really a Surprise Anymore...: kill 50 mimics in total.
Valued Regular: Increase your discount to 100
Thorough Cleanse: kill every single enemy on a floor before killing the boss.
Overkill: Get one of your weapon damage stats to 100
Guaranteed Gut Punch: Achieve 100% crit chance on any weapon.
Illusionist: raise your evasion stat to 70.
Leprechaun: Max out your luck stat.
You're Supposed to Eat That!: kill an enemy by throwing food at them.
Accidents Happen: Kill 10 enemies indirectly (spikes, thorn grass, arrow traps, etc.)
if you can think of more lemme know and I'll put them up here.