tl;dr: A Mark that increases in power every usage of the mark itself. It passively makes the player instantly kill enemies below a certain HP threshold, which is more effective against bosses
30 kills to charge, using it will increase the bold number below by 2. The number can be increased indefinitely, as long as the player doesn't get a different mark, in which case the number is set back to 0.
If you get an enemy below or at 2 HP (1 heart) using any of your weapons, or their relic effects, like Forge Embers, the enemy is killed instantly. This is 200% effective on bosses and anything spawned in the boss rooms.
So, for example, if the mark was used 3 times in total, the execution threshold will be 2 + 2*3, which is equal to 8 HP (4 hearts), increased to 16 HP (8 hearts) against bosses and their minions.
The numbers can be changed, as this is only an example. However, it would be good if it was a mark, not a relic, to get that usage upgrade dopamine, and also an opportunity to make some cool particle effects without suddenly jumpscaring the player!