I got Masa and Mune in the same run expecting them to combine, I'm doing a big strength game and got the strength buff one first. I picked up the dex buff one expecting a combination but they didn't and now my strength has taken a massive hit as a result, I wouldn't have picked it up if I had know this was the case.
Please let me know if this is how it was intended or if this is a bug since the game is so new.