If you select Sacrifice of the Flesh, and then afterwards select the Ascend Follower Ritual after the first sacrifice, the game will softlock when you select a follow to ascend.
This doesn't appear to happen if you do this in the reverse order, or only select the Ascend Follower Ritual alone. Please check the video I posted below to see the bug in action.
Version: 1.0.1.46 (Also happened in the previous version)
If you select Sacrifice of the Flesh, and then afterwards select the Ascend Follower Ritual after the first sacrifice, the game will softlock when you select a follow to ascend. (You can pause during this though)
This doesn't appear to happen if you do this in the reverse order, or only select the Ascend Follower Ritual alone.
Version: 1.0.1....
I would reinstall too just in case, thank you for reporting though!