I was printing some boxes for storage as the print quality slowly worsened between prints, mostly with walls being less flush. Eventually, one print just absolutely borked. I printed a test cube to see if it was just a slice, and it was similarly borked.
I went ahead and re-level'd the bed, tightened the X and Y belts, recalibrated my E-steps, and replaced the extruder tip. While most of the big issues are gone, the uneven finish is still there.
I use CURA for slicing, and the only modification to the printer has been a textured bed.