I found this Kovarex design, that uses pair of splitters directing flow of uranium as it goes from source to target.
U235 and U238 seems to have to be on one side of belt.
I think it could start after uranium processing, go trough chain of kovarex, then feed assembler. Some of U238 could be gathered from uranium reprocessing.
Then main loop goes back to starting point.
Does it require beacons if you use multiple GW of nuclear power?
Or beacons are necessary only if you apply uranium liberally - uranium ammo and nukes?