Patched-conics orbital mechanics like in KSP with each planetary body moving independently of each other in the sky on rails.
For the scale of the game, I feel this should be tweaked such that gravity is way higher then in real life (specifically, it should drop off much slower such that higher orbits still have you moving at a good speed), such that an orbit should take no longer then 6-7m around an average sized planet and moving between planets should ideally only take around 15m when a transfer window is available (obviously this would take much longer otherwise)