As it stands right now, there are several effects that effect the "nearest enemy", such as those on vestiges, ascensions, and most notably Godkeeper's spear smite effect. But as of right now, there's not really anyway to tell which enemy is considered by the game to be the "nearest".
I'm wondering if maybe a small highlight or indicator of some sort could be applied to what the game considers to be the nearest enemy? And perhaps, this could be extended to when you're placing or hovering over a Godkeeper spear, it changes the highlight to be on the enemy nearest to the spear. Something like that!!
Also, vestiges (and other things??) that have the effect of "on turn start, <do X effect> to the nearest enemy" should really be changed to say "to a random enemy". Due to enemies moving around a bunch between turns, this oftentimes feels entirely random what enemy will end up being the nearest, except in niche cases of enemies that don't move at all like how the Captor doesn't move, etc.