certain visual effects are too intense. while the game does open up with the disclaimer about graphics, i do think that there should be an option to make it more light (and accessible) beyond the flashing vfx setting.
certain weapons like vandalier, no future, etc are especially eye-straining when area and cooldown buffs are applied. i think that for many people, it'd help to have an option like this not for their eyes but to actually see the enemies as well :P
made a post on this a while back, i think it's still relevant: https://www.reddit.com/r/VampireSurvivors/comments/18sk6ny/new_players_talk_about_graphics/