unique spire
im running an all bells game on the beta, I got a shellbo with a frostwolf charm, the charm said it clears after triggering but it cleared without me playing it
it came up in a early run and i didnt use it, second time i drew it i got it without the debuff
vital basalt
I presume that any card that goes into the discard pile gets cleared of the debuffs. The same thing with companions.
median zinc
^