You have a few things going on here. Let’s dissect them.
You’re correct you don’t need a U2C. I would recommend removing it from the CANbus.
Am I right in assuming this all started after updating klipper?
When you run the MAKE FLASH command are you getting the DFU error at the end of the process?
Since your UUIDs are already assigned klipper will report back 0 UUIDs.