Buccaneer cannot open secret rooms,sometimes doesn't destroy resource rocks (leaves,honey,etc.), and most importantly does NOT destroy the tentacles during the final boss leading to unavoidable damage (at times/If you don't have a secondary gun) during the final boss.
(I say at times because you can stand in the top right/left corner of the second phase of the last boss and avoid the tenticale attack that way.) (I'll get an image of that soon)
Another bug was when I took a screenshot of the game during the final boss it just insta-killed me I had 2 shields and a single health left (no Idea how to replicate this.)
The Rail gun also cannot open secret rooms (haven't tested if it can destroy the tentacles.)
The Hydra paired with Time-based rounds DESTROYS bosses (especially Hell-o Kitty.)
Welp that was all I found so far have a good day. (Most recent verison 10/4/2023)