Do note that this guide is solo-centric in mind but group sales are highly optimal within these locations. Also, note that this guide is done in consideration with potential discounts whenever Rockstar does so (note all are base prices).
In my opinion, it is better to have your businesses spread throughout since sales will have you bounce around the map and Terrorbyte MCT exists as well as the Arcade to resupply and restock.
Document Forgery Office
Textile City Office - $1,235,000
Equipment Upgrade = $550,000
Staff Upgrade = $195,000
Security Upgrade = $285,000
No. of Resupplies Needed = 2x ($150,000 total)
Time to Full = 2 hours 15 minutes (max up)
Total Initial Expenses = $2,265,000
Weed Warehouse
Downtown Vinewood - $1,358,500
Equipment Upgrade = $990,000
Staff Upgrade = $273,000
Security Upgrade = $313,500
No. of Resupplies Needed = 2.5x ($195,000 total)
Time to Full = 4 hours 40 minutes (max up)
Total Initial Expenses = $2,935,000
Counterfeit Cash Factory
Grand Senora Desert - $845,000 (FREE for Criminal Enterprise Pack)
Equipment Upgrade = $880,000
Staff Upgrade = $273,000
Security Upgrade = $456,000
No. of Resupplies Needed = 3x ($225,000 total)
Time to Full = 4 hours 40 minutes (max up)
Total Initial Expenses = $2,454,000 or $1,609,000 for the pack bundle
Meth Lab
Grand Senora Desert - $910,000
Equipment Upgrade = $1,100,000
Staff Upgrade = $331,500
Security Upgrade = $513,000
No. of Resupplies Needed = 3x ($225,000 total)
Time to Full = 6 hours (max up)
Total Initial Expenses = $2,854,500
Cocaine Factory
Morningwood - $1,852,500
Equipment Upgrade = $935,000
Staff Upgrade = $390,000
Security Upgrade = $570,000
No. of Resupplies Needed = 4x ($300,000 total)
Time to Full = 5 hours (max up)
Total Initial Expenses = $3,747,500
TOTAL EXPENSES FOR ALL BUSINESSES + UPGRADES = $14,256,000