I've tried using 2 different USB drives, I've looked through the BIOS to hit every thing I can find about using fast or secure boot, I've tried different USB ports (USB2.0 and USB3.0), and I've tried removing my GPU and using the integrated graphics on the motherboard since I read that Mint sometimes struggles with Nvidia devices (although the GPU is about 5 years old at this point). I have also tried running the memory test to see if there were any detectable hardware issues but nothing came up.
When I set the USB drive as the boot device and from the GRUB menu select Linux Mint 22.2 (either normally or in compatibility mode) I have noticed the process hangs/seems to loop at "job gpu-manager.service" (I'll need to get the whole message when it hangs) and after about 10-15 minutes of trying to boot I usually give up and have it reboot. This lead me to believe the GPU was causing the issue, but I am not sure. While most of this hardware is a bit older, it was very good when I built it (i7 Sandy Bridge processor, 32 GB of DDR3, 2 TB of SSD) and I'm not quite ready to donate it all away just yet.
It's been about 15 years since I've used Linux Ubuntu, and while I'm very much a Windows guy, this PC is destined to be a spare for when I'm not working and to get back into Linux a bit (if I can ever get it running)