#Fertilizer after lab upgrade
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tldr: fertilizer I or II is worth it
Feetilizer I & II is purchasable from Sam's general store or Ling's lab, so it's easier to do. Whereas III you need to craft it, which is not worth the hassle
Take cactus for example
Cactus mead price based on quality is:
5470 / 6280 / 7090 / 8170 / 10870
Fertilizer II cost 70 gold, it's a really good trade for the final product
You can however, use fertilizer III for the greenhouse. Regrow crops and fruit plants live forever in the greenhouse, thus Can continuously produces crops/fruit.