I've had similar issues with both previous betas and alphas where the game will not scale correctly to the screen if the windows scaling is not set to 100% which is a big issue a lot of displays' defaults aren't 100% scaling. Alt tabbing in and out of the game while on full screen causes a lot of flickering and makes interacting with other windows a lot more difficult as compared to the borderless mode.
example of the scaling issue on a 1440p display at 125% scaling