So with the targeting change, if I understand it units will be able to acquire targets more often, and as a result, many anti-spam units will be effectively getting buffed, most notably razorback.
I think it would be nice if Karganeth, as the core counterpart to razorback, got some small changes that would also help against spam, as core doesn't have great mid-late game offensive options against mass spam.
If karganeth missiles had a slightly larger aoe and a small amount of impulse, I think that would be nice. It wouldn't change its single target damage, but might add to its pushing utility.
Of course, this is a hypothetical future change, based off speculation that razorback will be massively powerful against spam in the future and that karganeth will not etc, but I thought it might be worth thinking about.