So Before you Start a Run you have to set up that architect buff stuff right, well i set the ones i wanted and decided to start the run but it turned out it didn't start and only took the materials, i kinda tried to start it 3x and it took everything without any change so i restated and they just gone...
#Lost Materials Trying to Start Run
robust canopy
dawn wave
This occurred as host in multiplayers, with 2-3 clients.