It’s all about personal preference and whether you prefer a more offensive or defensive build. There are situations where one will be better than the other, so building so you can swap isn’t a terrible idea.
#liar's handshake vs assassin cowl
mortal mural
floral tundra
assassins allows you to never worry about your hp, yes does less dmg but most ads die in 1 shot anyway and one two punch shotty makes more tanky ones easy as well. Its what i used in spire solo flawless