Hi I m trying to use the QT Py ESP32 S2

[tawny comet]

The TX/RX shown on the Pinout [1] (GPIO5 and GPIO16) do work, but not over USB-C.

[1] https://learn.adafruit.com/assets/107493

Not sure the question makes sense at all, as I don't understand USB-C or how it enables UART. If the PCB helps, it's here [2]

[2] https://github.com/adafruit/Adafruit-QT-Py-ESP32-S2-PCB

(I did try to use the USB D+ and D- as TX/RX and vice versa, but that did not work.)

OK, from this USB-C pinout diagram [3] ist looks as if D+/D- are different from TX/RX.

[3] https://www.allaboutcircuits.com/technical-articles/introduction-to-usb-type-c-which-pins-power-delivery-data-transfer/