Alright everyone, to expand this as quickly as possible, I present to you;
Practically Hulk
Bruce Banner
Bruce Banner is a renowned scientist graduated from Harvard in Biological engineering. His noted work on the cure for Diabetes led to him being drafted into an experimental project for the US army; The goal was to create a way of numbing the pain receptors of the brain with an on/off switch modality in preparation for a possible upcoming war.
Mr Banner's first thought was obviously to go with adrenaline, but making the effects of the hormone permanent until further notice was an exciting challenge for him. Eventually the doctor managed to synthethize a protein capable of stimulating the brain into releasing adrenaline until another source overrides it, essentially turning andrenaline shots into on/off buttons.
What Banner didn't account for is that adrenaline can be released naturally by the brain when stressed, and so by starting human trials on himself he effectively became a ticking stress bomb
Due to the erratic nature of an angered person on adrenaline, Dr. Banner constantly gets intravenously injured, leading to his blood clotting inside his body and eventually killing the area, which starts the process of Necrosis, however due to his remarkable physique his body is able to slowly recover soon after the minute-long anger episodes he has.
All of these factors have led to his new nickname: "The Hulk". Banner is now being kept in a psych ward with constant testing being done to revert his condition