So I put together a little something. It's purely for me, and I main DPS. I will not be using this mess if I ever decide to heal for very obvious reasons. Basically I just wanted things to feel a bit more connected instead of randomly floating around, so I started connecting them with Custom Text (brackets and dashes). Then I added corner borders with some Unicode Characters (still custom text). Then I slapped down some Empty Clickthrough Actionbars with a transparent backdrop and Low Strata to act as filler for when those UI Elements weren't present (ie: no target, no target of target, no pet summoned, etc) so that the connecting bits had something of substance to latch onto.
I like how it turned out. Makes it feel a little bit like the Starcraft Mission Briefing screens or something.
First Picture is everything filled and castbars rolling.
Second Picture (first comment) has some sections unfilled to show off the Actionbar Backdrop nonsense.
(Edit: Just noticed the Pet Bar on the right. I'll be disabling that as I'm a Shaman not a Hunter.)