Game actually runs fine 30-40 fps and was able to make it through and complete medical, but after entering research and making it about half way through the game starts crashing spitting up this error.
LowLevelFatalError [File:Unknown] [Line: 198]
Unreal Engine is exiting due to D3D device being lost. (Error: 0x887A0006 - 'HUNG')
I suspect this is also a problem with many other sections further in the game.
Many other Unreal Engine 4 games run fine on integrated graphics without crashing so it should also be the case for this game.
System Specs
i5-7300U CPU
HD Graphics 620
16GB of Ram
256GB SSD