Makes the game's Big Quests harder. This can be through making the requirements stricter, or by increasing the requirements needed.
Movin' On Up: Money required becomes 75 per floor (225 per district, 1125 for the entire run)
Power Struggle: Owners of non-hideouts with generators in them will gain better weapons and spawn more property owners.
Turf War: An extra roaming enemy gang will spawn every floor. Enemy gangsters may replace Uptown NPCs.
Undiscerning Looting: Chest/Safe requirement is upped to 5. (if there are less than 5 chests/safes in the level you'll just have to rob of all em)
The New Hotness: Non-friendly NPCs will refuse to give up the hot item, so you must gain it through whatever other means you can.
Hack the Planet: 12 Cop Bots are spawned.
Purveyor of Peace: You must kill less than 15 people in the run. Other values are halved accordingly
Ethical Experiments: All NPC types that are your target will have a ranged weapon if possible.
Hairy Justice: Owners of buildings with gorillas in them will gain better weapons and spawn more property owners.
Law Abiding Law Enforcer: Marks per floor raised to 14.
Mythical Matchup: 2-3 Werewolves spawn per floor.
The Undefeated Champ: Your opponent will gain a random positive status effect on fight start. (no it can't be invincible or invisible)
Silent But Deadly: You have 2-3 assigned targets now.
Last Comic Standing: Tell jokes to 60% of the floor (raised from 40% according to the wiki)
Harmless Pranks: The game will prioritize picking objects in greater quantities, and objects that are indoors.
Seeds of Chaos: "Weaker" classes are prioritized as the class you need to possess
Sobriety is for Suckers: No more than 12 withdrawals for the run, no more than 2 withdrawals per district, no withdrawals on a floor.
Satiate that Bloodlust!: Kill 7 or more people while transformed.
Acquired Tastes: Eat 3 (if available) of the NPC type.
Catch 'Em All!: You need to do it with 3 of the NPC now.
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