From what I understand, there are games that were only released for MSX2+ and MSX Turbo R. This site I found goes into more detail: https://www.msx.org/wiki/MSX_for_beginners
Welcome to the MSX for beginners guide. The aim of this guide is to provide information to people who are new to MSX, and are interested in the system. The focus of this document is mostly on (retro) gamers, but each section has links to items with related information for a more in depth look.