This is pretty minor, but I had 5 eternal joker stencils (polychrome) and I came across an Ankh card. For some reason, it allowed me to click “Buy & Use” when I had no room for an extra joker.
I clicked it to see what would happen. It took the money and failed to activate the Ankh. The Ankh was stuck in this spot on the screen for the rest of the run (including the Shop, Blind Selection, and Blind screens).
Probably some kind of edge case since Stencil is counted as taking up a joker slot in some contexts and not in others, and possibly involving the eternal property.