Some ideas i have about bosses who punish you for playing some specific runs
The Bullseye, Ante 1-4
If total score >=1,5X Required chips, destroy one random Joker
The Rust, Ante 3+, only appear if your deck have at least 5 steel
Steel cards are debuffed
The Colorblind, Ante 3+
Card suits are hidden
NOTE: sorting by suit does not work, played hand will not be recognised as Flush until played. Wild card will be seen as usual
The Procrastinator, Ante 4+, only appear if you won at least 4 blinds in 1 hand
All hands are capped at 45% required chips, start with at least 3 hands (in case you have less)
The Divisor, Ante 4+, only appear if you have at least 3 Jokers with effects +Chips or +Mult
+Chips and +Mults on Jokers are divided by two
The Tax, Ante 5+, only appear if you have more then 20 dollrs when entering new Ante
Owned $/30 cards are debuffed
NOTE: unaffected by Oa6.
The Eclipse, Ante 5+, only appear if you have at least 1 hand type lvl 10 or more
If played hand lvl >9, divide it level by half (rounded up)
The Doom, Ante 6+, only appear if your full deck have at least 12 listed probabilities or at least 2 in your Jokers
Half all listed probabilities
The Brothers, Ante 6+, only appear if you have multiple of same Joker
Only 1 Joker of same kind can trigger
The First, Ante 6+, only appear if you have ways to score cards more then once
Cards only score once
All next are Ante 8
The Shopaholic, only appear if you have bought at least 7 Vouchers
Blind size scales with bought Vouchers and with cost of all Jokers and Consumables
NOTE: exact formula i suggest is Base X MAX(Total Joker + Consumable Cost/20);1) X (Vouchers bought/4). So, if you have 40 total cost and 8 Vouchers, it will be 8X base
The Hated
All suits but [suit] are debuffed
note: The Hated appear only if you have suit with 1-4 cards (NOT 0). One of such suits will be choosen and locked, you will see it in Blind selection menu
The Commoner
Enchanced cards have all their values halfed