I kinda worry that some of the most fun vanilla jokers will become very diluted in the joker pool when you play with a few mods active, so I've tried to come up with alternatives to some of my favorite vanilla jokers that do kinda the same thing as them, but different enough to feel unique.
Suggesting these as jokers for a mod for people who want to play with mods, but don't want the experience to stray too far away from vanilla.
Wayward joker (Vagabond)
Creates two random consumables if hand is played with $0 or less.
(One card will always be tarot, while the other is completely random and can also land on modded consumables)
Loan shark (Credit card)
Doubles all money gained. Money will be reduced by the amount spent this ante upon starting boss blind.
Succubus (Vampire)
X1 mult. Gains X0.75 mult for each scoring card with an edition or seal. Removes editions and seals.
Accountant (Fortune teller)
Gains +5 chips for each consumable used this run.
Plush dice (Oops all 6’s)
All probability rolls has an equal chance of triggering an additional time.
Switch joker (Riff raff, Invisible Joker) (rare)
Once per shop: Sell a joker for $0 and receive a joker of the same rarity (also applies to self as a one-time use, but you get to roll for a rare)