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SR5, putting it together with examples
See the graphic for a summary and examples.
The following are some rough numbers to shoot for. Note that these are just general guidelines and not firm requirements. There's 18 individual monsters each contributing something and everyone is going to have different exact teams and setups. Some teams may work with less than the suggested numbers, but at the same time, hitting all the suggested numbers doesn't guarantee your team will work either.
Frontline: 220k eHP, with at least 1500 def after lead and towers
Backline: 120k eHP (yes this means that your squishy DD like Ardella may need a slot 2 or slot 6 HP% main rune)
Healers/cleansers should have at least 200 speed, the more the better. They will benefit from 100 res and Vio, although neither are absolutely necessary. If you choose to get res, go for 100 or don't bother with any at all. If your cleanser has exactly 200 speed, no res, and is not on vio, then it is NOT meeting the stat guidelines.
Vio is not as helpful on other units, but won't hurt either. Forcing Vio at the cost of stats is always detrimental though.
It's ok if your damage dealers are not 100 CR. It's a good goal to aim for but since you have sustain, you're only look for average damage output and a missed crit won't kill you. 150-160 speed is enough for most damage dealers.
You should expect 1:15 - 1:30 runs at the start. If it takes longer you need more damage. Eventually this style of team can go all the way down to 35-40 sec average.
It won't hurt to run a bit of R4 first if you just need a bit extra of stats. You can get a lot of progress really fast with basic grinds on most of your runes.
Here are stats of my monsters, compare them to yours if things aren't working: https://ibb.co/album/0hdwWY
eager berry
keen quarryBOT
sacred wolf